There has long been a debate as to whether or not Nurse Practitioners (NPs) and Physician Assistants (PAs) should have autonomy to practice on their own. This debate has intensified as telemedicine has begun to play a larger role in healthcare. While NPs and PAs argue that restrictions requiring physician supervision create limitations on the volume of care, physicians counter that oversight is necessary to ensure that patients receive the best care possible. With so much information on both sides of the issue, we compiled a list of pros and cons to the argument for NP and PA autonomy.